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<< Semaglutide Injection / Safety and Precautions

Safety & Precautions

Semaglutide Injection

Compounded semaglutide is a prescription medication used for chronic weight management in adults with obesity or overweight with at least one weight-related condition. It is not FDA-approved, but can be prescribed under federal law by a licensed provider based on your medical evaluation.

Who Should Not Use It:

  • Anyone with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia type 2 (MEN 2)

  • People with a known allergy to semaglutide

  • Patients with type 1 diabetes or a history of pancreatitis

How It Works:
Semaglutide is a GLP-1 receptor agonist that helps control appetite, improve blood sugar, and support weight loss. It is administered once weekly via subcutaneous injection in the stomach, thigh, or upper arm.

Important Warnings:

  • Possible risk of thyroid tumors, pancreatitis, gallbladder issues, kidney injury, low blood sugar, or increased heart rate

  • Report any lumps in the neck, severe abdominal pain, vision changes, or allergic reactions to your provider immediately

  • Avoid use during pregnancy or breastfeeding

Side Effects:
Common: nausea, diarrhea, vomiting, constipation, headache, fatigue, abdominal discomfort
Serious: thyroid tumors, pancreatitis, gallbladder disease, severe hypoglycemia, kidney injury, serious allergic reactions, or mental health changes

Precautions:
Tell your provider about all medications, supplements, and medical conditions before starting semaglutide. Do not share needles or adjust your dose without guidance.

Reporting Side Effects:
You can report side effects to FDA MedWatch at 1-800-FDA-1088 or online at www.fda.gov/medwatc

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